Desinfektan dan sifat antibakteri oregano oil (minyak oregano) pertama kali diketahui orang Yunani kuno di mana mereka sering menggunakannya untuk mengobati infeksi bakteri pada kulit atau luka, dan juga digunakan untuk melindungi makanan dari bakteri.
Oregano merupakan tumbuhan yang tumbuh di ketinggian atau pegunungan, sehingga mendapatkan nama “Oregano”, yang berarti “Delight of the Mountains”.
Oregano essential oil diekstrak melalui distilasi uap dari daun oregano segar, yang memiliki nama ilmiah Oreganum vulgare.
Komponen utama dalam oregano adalah Carvacrol, Thymol, Cymene, Caryophyllene, Pinene, Bisabolene, Linalool, Borneol, Geranyl Acetate, Linalyl Acetate dan Terpinene.
Seiring dengan sifat antimikroba, minyak ini juga memiliki banyak sifat obat.
Oregano oil (minyak oregano) secara tradisional digunakan dalam salah satu dari tiga cara.
Pertama, digunakan secara ‘aromatically’, yang merupakan metode paling populer seiring metode aromaterapi yang semakin dikenal luas.
Kedua, Anda dapat mengoleskannya secara topikal ke kulit, atau melalui minyak carrier seperti minyak kelapa.
Akhirnya, oregano oil bisa digunakan secara internal (ditelan) dalam jumlah yang sangat kecil sebagai suplemen makanan, biasanya ketika diencerkan dalam madu atau minuman non-susu lainnya.
Manfaat Oregano Oil
Dirancang khusus untuk infeksi bakteri, antibiotik menjadi favorit banyak dokter untuk mengatasi berbagai keluhan pasien.
Tapi manfaat oregano oil (minyak oregano) terbukti lebih unggul atas beberapa antibiotik, tanpa efek samping yang berbahaya.
Sayangnya, berbagai antibiotik yang diresepkan saat ini memiliki berbagai efek samping seperti menyebabkan resistensi antibiotik, membunuh bakteri baik (probiotik), mengurangi penyerapan vitamin dan merusak lapisan pencernaan sehingga menyebabkan usus bocor.
Pada dasarnya, mengambil pendekatan spektrum luas menggunakan antibiotik mirip dengan menjatuhkan bom nuklir, alih-alih menugaskan tim operasi khusus untuk menghancurkan musuh.
Kabar baiknya, terdapat alternatif alami luar biasa untuk resep antibiotik yaitu oregano oil.
Oregano oil (minyak oregano) mengandung dua senyawa kuat yaitu carvacrol dan thymol yang memiliki sifat anti-bakteri dan anti-jamur yang kuat.
Masalah dengan Resep Antibiotik
Terlalu sering menggunakan antibiotik dan obat resep spektrum luas ketika sebenarnya tidak terlalu diperlukan, dapat menyebabkan berbagai masalah.
Dalam jangka panjang, kondisi ini dapat membuat obat kurang efektif terhadap bakteri karena meningkatkan sifat resisten bakteri terhadap antibiotik.
Selain itu, antibiotik bisa membunuh bakteri baik dalam tubuh (probiotik), yang membantu pencernaan makanan, memproduksi vitamin dan melindungi dari infeksi, serta fungsi lainnya.
Dalam sebuah studi di Amerika Serikat, dari antibiotik yang diresepkan dokter, 60% nya merupakan antibiotik spektrum luas.
Sebuah studi serupa pada anak-anak, ditemukan pula bahwa 50% antibitoik yang diresepkan pada anak-anak merupakan antibiotic spectrum luas, terutama yang digunakan untuk masalah pernapasan.
Manfaat Oregano Oil, Tak Terbantahkan
Merupakan keluarga mint (Labiatae), oregano oil bukan apa yang biasanya digunakan untuk menyedapkan makanan.
Ditemukan di Mediterania, medical grade oregano disuling untuk mengekstrak essential oil (minyak esensial) dan mempertahankan senyawa penyembuhan yang dimilikinya.
DIbutuhkan sekitar 1000 gram oregano untuk memproduksi 1 gram minyak oregano, komoditas yang dianggap berharga selama lebih dari 2.500 tahun dalam pengobatan tradisional.
Senyawa penyembuhan utama dalam oregano, carvacrol, merupakan komponen paling penting yang menyumbang khasiat oregano.
Terdapat lebih dari 800 studi referensi yang mengulas khasiat carvacrol di PubMed, yang merupakan database no. 1 tentang literature sains ilmiah.
Berikut adalah beberapa kemampuan pengobatan yang dimiliki oregano:
- Infeksi bakteri
- Infeksi jamur
Journal of Medicinal Food pernah menerbitkan sebuah studi yang mengevaluasi aktivitas antibakteri oregano oil terhadap 5 jenis bakteri jahat.
Studi menunjukkan oregano oil memiliki kemampuan signifikan melawan 5 spesies bakteri berbahaya.
Menariknya, aktivitas tertinggi teramati terhadap bakteri E. Coli, yang menunjukkan oregano oil harus secara rutin digunakan untuk meningkatkan kesehatan pencernaan dan mencegah keracunan makanan yang mematikan.
Sebelumnya, para peneliti dari Pakistan menerbitkan hasil yang sama di jurnal Revista Brasileira de Farmacognosia, sekaligus membuktikan kemampuan oregano oil untuk membunuh sel-sel kanker dari berbagai jenis!
Oregano Oil Lebih dari Sekedar Antibiotik
Puluhan penelitian lain mengkonfirmasi fakta oregano oil dapat digunakan sebagai pengganti antibiotik untuk sejumlah masalah kesehatan.
Sedang penelitian lain mendukung fakta bahwa oregano lebih dari sekedar antibiotik biasa, melainkan antibiotik alami terkuat.
Misalnya, sebuah studi dari European Review for Medical and Pharmacological Sciences menemukan oregano membantu melindungi efek samping akibat methotrexate (MTX).
Penelitian menunjukkan carvacrol mampu melindungi terhadap toksisitas methotrexate pada tikus.
Methotrexate (MTX) adalah obat yang biasa digunakan untuk mengobati berbagai macam masalah dari kanker hingga rheumatoid arthritis.
Diketahui memiliki efek samping yang berbahaya, peneliti dari Turki mengevaluasi kemampuan oregano oil memberikan efek perlindungan penuh terhadap MTX.
Dengan mengevaluasi berbagai penanda pada saraf sciatic tikus, diamati untuk pertama kalinya bahwa carvacrol menurunkan respon inflamasi pada tikus yang diberi MTX.
Dalam cara yang sama, peneliti dari Belanda bahkan menunjukkan oregano oil juga dapat “mencegah pertumbuhan bakteri dan kolonisasi di usus besar selama terapi zat besi secara oral.”
Digunakan untuk mengobati anemia, terapi zat besi secara oral diketahui menyebabkan serangkaian masalah pencernaan seperti mual, diare, sembelit, mulas dan muntah.
Perlu dicatat bahwa dua penelitian ini memberikan harapan kepada orang-orang yang mengalami berbagai efek yang menyertai penggunaan obat-obatan dan intervensi medis.
Penggunaan Oregano Oil, Peringatan
Anda mungkin bertanya, bagaimana agar minyak oregano bisa digunakan dengan aman? Pada titik ini, belum terdapat ketentuan yang jelas.
Satu hal yang pasti, karena kemampuan kuat yang dimilikinya, penggunaan oregano oil harus dilakukan secara hati-hati.
Saat mengambilnya secara internal, oregano oil harus diencerkan dengan air atau dicampur dengan minyak kelapa.
Herbal oregano kering biasanya bisa digunakan oleh wanita hamil, tetapi ketika menggunakan oregano oil maka penggunaannya harus dilakukan secara hati-hati.
disadur : https://www.atsirich.com/21/manfaat-oregano-oil-sebagai-antibiotik-alami-terkuat/
9 Benefits and Uses of Oregano Oil
Oregano is a fragrant herb that’s best known as an ingredient in Italian food.
However, it can also be concentrated into an essential oil that’s loaded with antioxidants and powerful compounds that have proven health benefits.
Oregano oil is the extract and, although it’s not as strong as the essential oil, it appears to be useful both when consumed or applied to the skin. Essential oils, on the other hand, are not meant to be consumed.
Interestingly, oregano oil is an effective natural antibiotic and antifungal agent, and it may help you lose weight and lower your cholesterol levels.
Botanically known as Origanum vulgare, oregano is a flowering plant from the same family as mint. It’s often used as an herb to flavor food.
Although it’s native to Europe, it now grows all over the world.
Oregano has been popular ever since the ancient Greek and Roman civilizations used it for medicinal purposes. In fact, the name oregano comes from the Greek words “oros,” meaning mountain, and “ganos,” meaning joy or delight.
The herb has also been used for centuries as a culinary spice.
Oregano essential oil is made by air-drying the leaves and shoots of the plant. Once they’re dried, the oil is extracted and concentrated by steam distillation (1).
Oregano essential oil can be mixed with a carrier oil and applied topically. However, it should not be consumed orally.
Oregano oil extract, on the other hand, can be produced via several extraction methods using compounds like carbon dioxide or alcohol. It’s widely available as a supplement and can often be found in pill or capsule form (2Trusted Source).
Oregano contains compounds called phenols, terpenes, and terpenoids. They have powerful antioxidant properties and are responsible for its fragrance (2Trusted Source):
- Carvacrol. The most abundant phenol in oregano, it has been shown to stop the growth of several different types of bacteria (3Trusted Source).
- Thymol. This natural antifungal can also support the immune system and protect against toxins (4).
- Rosmarinic acid. This powerful antioxidant helps protect against damage caused by free radicals (5Trusted Source).
These compounds are thought to underlie oregano’s many health benefits.
Here are 9 potential benefits and uses of oregano oil.
Oregano and the carvacrol it contains may help fight bacteria.
The Staphylococcus aureus bacterium is one of the most common causes of infection, resulting in ailments like food poisoning and skin infections.
One particular study looked at whether oregano essential oil improved the survival of 14 mice infected with Staphylococcus aureus.
It found that 43% of the mice given oregano essential oil lived past 30 days, a survival rate nearly as high as the 50% survival rate for mice that received regular antibiotics (6Trusted Source).
Research has also shown that oregano essential oil may be effective against some potentially antibiotic-resistant bacteria.
Although more human studies on the effects of oregano oil extract are needed, it contains many of the same compounds as oregano essential oil and may offer similar health benefits when used as a supplement.
SUMMARYOne mouse study found oregano essential oil to be almost as effective as antibiotics against common bacteria, though much more research is needed.
Studies have shown that oregano oil may help lower cholesterol.
In one study, 48 people with mildly high cholesterol were given diet and lifestyle advice to help lower their cholesterol. Thirty-two participants were also given 0.85 ounces (25 mL) of oregano oil extract after each meal.
After 3 months, those given the oregano oil had lower LDL (bad) cholesterol and higher HDL (good) cholesterol, compared with those who were just given diet and lifestyle advice (9Trusted Source).
Carvacrol, the main compound in oregano oil, has also been shown to help lower cholesterol in mice that were fed a high fat diet over 10 weeks.
The mice given carvacrol alongside the high fat diet had significantly lower cholesterol at the end of the 10 weeks, compared with those that were just given a high fat diet (10Trusted Source).
The cholesterol-lowering effect of oregano oil is thought to be the result of the phenols carvacrol and thymol (11Trusted Source).
SUMMARYStudies have shown that oregano may help lower cholesterol in people and mice with high cholesterol. This is thought to be the result of the compounds carvacrol and thymol.
Antioxidants help protect the body from damage caused by free radicals.
It’s thought that free radical damage plays a role in aging and the development of some diseases, such as cancer and heart disease.
Free radicals are everywhere and a natural product of metabolism.
However, they can build up in the body through exposure to environmental factors, such as cigarette smoke and air pollutants.
One older test-tube study compared the antioxidant content of 39 commonly used herbs and found that oregano had the highest concentration of antioxidants.
It found that oregano contained 3–30 times the levels of antioxidants in the other herbs studied, which included thyme, marjoram, and St. John’s wort.
Gram per gram, oregano also has 42 times the antioxidant level of apples and 4 times that of blueberries. This is thought to be mostly due to its rosmarinic acid content (12Trusted Source).
Because oregano oil extract is very concentrated, you need much less oregano oil to reap the same antioxidant benefits as you would from fresh oregano.
SUMMARYFresh oregano has a very high antioxidant content. In fact, it’s much higher than that of most fruits and vegetables, gram per gram. The antioxidant content is concentrated in oregano oil.
Yeast is a type of fungus. It can be harmless, but overgrowth can result in gut problems and infections, such as thrush.
In test-tube studies, oregano essential oil has been found to be effective against five different types of Candida, such as those that cause infections in the mouth and vagina. In fact, it was more effective than any other essential oil tested (14Trusted Source).
Test-tube studies have also found that carvacrol, one of the main compounds of oregano oil, is very effective against oral Candida (15Trusted Source).
High levels of the yeast Candida have also been associated with some gut conditions, such as Crohn’s disease and ulcerative colitis (16Trusted Source).
A test-tube study on the effectiveness of oregano essential oil on 16 different strains of Candida concluded that oregano oil may be a good alternative treatment for Candida yeast infections. However, more research is needed (17Trusted Source).
SUMMARYTest-tube studies have shown that oregano essential oil is effective against Candida, the most common form of yeast.
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Oregano may benefit gut health in a number of ways.
Gut symptoms like diarrhea, pain, and bloating are common and can be caused by gut parasites.
One older study gave 600 mg of oregano oil to 14 people who had gut symptoms as a result of a parasite. After daily treatment for 6 weeks, all participants experienced a reduction in parasites, and 77% were cured.
Participants also experienced a reduction in gut symptoms and tiredness associated with the symptoms (18Trusted Source).
Oregano may also help protect against another common gut complaint known as “leaky gut.” This happens when the gut wall becomes damaged, allowing bacteria and toxins to pass into the bloodstream.
In a study on pigs, oregano essential oil protected the gut wall from damage and prevented it from becoming “leaky.” It also reduced the number of E. coli bacteria in the gut (19Trusted Source).
SUMMARYOregano oil may benefit gut health by killing gut parasites and protecting against leaky gut syndrome.
Inflammation in the body is linked to a number of adverse health effects.
Research has shown that oregano oil may reduce inflammation.
One mouse study found that oregano essential oil, along with thyme essential oil, reduced inflammatory markers in those that had artificially induced colitis (20Trusted Source).
Carvacrol, one of the key components in oregano oil, has also been shown to reduce inflammation.
One study directly applied different concentrations of carvacrol to the swollen paws or ears of mice. Carvacrol reduced paw and ear swelling by 35–61% and 33–43%, respectively (21Trusted Source).
SUMMARYOregano oil and its components may help reduce inflammation in mice, though human studies are needed.
Oregano oil has been investigated for its painkilling properties.
One older study in mice tested standard painkillers and essential oils, including oregano essential oil, for their ability to relieve pain.
It found that oregano essential oil significantly reduced pain in mice, exerting effects similar to those of the commonly used painkillers fenoprofen and morphine.
The research proposed these results were likely due to the carvacrol content of oregano (22).
A similar study found that oregano extract reduced pain in rats, and that the response was dose-dependent, meaning the more oregano extract the rats consumed, the less pain they appeared to feel (23Trusted Source).
SUMMARYOregano oil may significantly reduce pain in mice and rats, exerting pain-relieving effects similar to those of some commonly used medications.
A few studies have indicated that carvacrol, one of the compounds of oregano oil, may have cancer-fighting properties.
In test-tube studies on cancer cells, carvacrol has demonstrated promising results against lung, liver, and breast cancer cells.
Although this is promising research, no studies have been carried out on people, so more research is needed.
SUMMARYPreliminary studies have shown that carvacrol — the most abundant compound in oregano oil — inhibits cancer cell growth and causes cell death in lung, liver, and breast cancer cells.
Thanks to oregano’s carvacrol content, oregano oil may aid weight loss.
In one study, mice were fed either a normal diet, high fat diet, or high fat diet with carvacrol. Those given carvacrol alongside their high fat diet gained significantly less weight and body fat than those just given a high fat diet.
Furthermore, carvacrol appeared to reverse the chain of events that can lead to the formation of fat cells (27Trusted Source).
More research is needed to demonstrate that oregano oil has a role in weight loss, but it may be worth trying as part of a healthy diet and lifestyle.
SUMMARYOregano oil may be beneficial for weight loss through the action of carvacrol, though human studies are needed.
Oregano oil extract is widely available in capsule and tablet form. It can be bought from most health food shops or online.
Because the strength of oregano supplements can vary, it’s important to read the directions on the individual packet for instructions on how to use the product.
Oregano essential oil is also available and can be diluted with a carrier oil and applied topically. Note that no essential oil should be ingested.
There’s no standard effective dose of oregano essential oil. However, it’s often mixed with around 1 teaspoon (5 mL) of olive oil per drop of oregano essential oil and applied directly to the skin.
Like other essential oils, keep in mind that oregano essential oil should not be consumed orally.
If you’re interested in taking oregano oil extract but currently taking prescription medications, make sure to consult your healthcare provider before adding it to your regimen.
In addition, oregano oil extract is not generally recommended for women who are pregnant or breastfeeding.
SUMMARYOregano oil extract can be purchased in pill or capsule form and taken orally. Oregano essential oil is also available and can be diluted with a carrier oil and applied to the skin.
Oregano oil extract and oregano essential oil are both relatively cheap and readily available.
Oregano is higher in antioxidants than most fruits and vegetables, and it’s packed full of powerful compounds called phenols.
Oregano also contains compounds that may be effective against bacterial and fungal infections, inflammation, and pain, among other conditions.
What are the benefits of oregano oil?
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Oregano oil is a product made from the oregano plant, Origanum vulgare. It contains a higher concentration of the helpful compounds that occur naturally in the plant.
This oil is available to use orally, unlike oregano essential oil, which is much more concentrated and used in aromatherapy. People should not take essential oils by mouth.
Whether a person applies it topically or takes an oral supplement, oregano oil may be helpful for a range of conditions.
Compounds in the oil have effective antioxidant and antimicrobial properties, which explain many of the benefits.
There are some risks and potential issues to consider before using oregano oil, and it may not be right for everyone. This article covers 10 of the most promising health benefits of oregano oil.
Oregano, or Origanum vulgare, is a small, bushy plant that belongs to the mint family. It is a familiar culinary herb in Italian dishes.
Oregano oil contains high levels of important compounds in its leaves and smaller stems. Oil manufacturers dry the leaves and stems, then steam-distill the plant matter to extract as many compounds as possible.
Oregano oil contains:
- carvacrol, the main active compound in oregano oil and a type of antioxidant called a phenol
- thymol, which may help protect against toxins and fight fungal infections
While oregano oil contains a significant amount, the compound thymol occurs most abundantly in thyme.
Oregano oil may have the following health benefits:
1. Fighting bacteria
Thanks to the high levels of carvacrol, oregano oil may help fight certain types of bacteria.
For instance, Staphylococcus is a common type of bacteria that causes staph infection. Some strains occur naturally in the body, but when the bacteria grow too quickly, it can cause bothersome symptoms.
Research shows that carvacrol is effective in eliminating the bacteria Staphylococcus aureus and Staphylococcus epidermidis, two common causes of infection.
Taking oregano oil supplements or rubbing it on the skin may help a person make use of these antibacterial effects.
Researchers are also exploring the use of oregano oil for antibiotic-resistant bacteria. The authors of a study in Frontiers in Microbiologyfound that a combination of oregano oil and silver nanoparticles effectively eliminated all the bacteria they tested.
2. Treating small intestine bacterial overgrowth (SIBO)
Oregano oil may help treat chronic bacterial issues, such as SIBO. People with SIBO experience gastrointestinal problems due to an overgrowth of certain bacteria in their intestines.
A 2014 study found that herbal remedies, including one that contained high levels of both carvacrol and thymol, were effective tools in treating SIBO.
Exploring the individual effects of each compound will require more research, but these initial findings may be promising.
3. Treating fungal infections
Oregano oil also appears to be a potent antifungal agent thanks to high levels of thymol.
Research from 2015 found thymol to be an effective treatment for common Candida fungal infections.
Candida causes several types of infections, including:
- oral thrush
- yeast infections
- infected toenails or fingernails
- athlete’s foot
The research was conducted in test tubes, however, and determining oregano oil’s effectiveness will require more studies in humans.
4. Providing antioxidants
Oregano oil is also a potent antioxidant. Antioxidants help protect the body from damage caused by oxidative stress and free radicals.
Thymol and carvacrol are powerful antioxidants that may help reduce oxidation. The researchers suggested that further studies explore safe doses for regular use.
5. Reducing inflammation
Some sources claim that oregano oil may help reduce inflammation. The compound carvacrol shows anti-inflammatory effects in both animal models and in vitro studies.
Research from 2017 looked at a variety of investigations into carvacrol’s anti-inflammatory effects.
In one study on mice, the compound prevented obesity by affecting the genes involved in inflammation. In another animal study, the compound reduced swelling.
While the results show promise, the researchers have called for more tests on humans to determine a safe dosage.
6. Healing wounds
Applying diluted oregano oil to the skin may help protect smaller cuts and scrapes on the skin as they heal.
Compounds such as thymol and carvacrol could protect these types of wound from bacterial infections.
7. Repelling insects
Both carvacrol and thymol may be effective insect-repellents. In 2017, researchers found that these compounds repelled some ticks and mosquitos. The research included test tube studies and those with human participants.
More research will help confirm this potential benefit, but rubbing diluted oregano oil on the skin may be a natural way to help repel insects.
8. Relieving pain
There is some evidence that oregano may be an effective pain reliever. An animal study found that an extract of oregano provided pain relief.
These results were dose-dependent — the more the animals took, the more pain relief they felt.
Importantly, the researchers used a water-based extract, so the oil may not provide the same results. More research in humans could help determine an appropriate dose.
9. Aiding weight loss
Oregano oil may also be a helpful tool for people looking to lose weight. Researchers have found that carvacrol, the main compound in oregano oil, disrupts part of the process that leads to the creation and accumulation of fat tissue.
More direct research may help provide additional evidence for these claims.
10. Fighting cancer
Some sources claim that oregano oil may help fight some cancers. One review notes that the essential oil from oregano helps prevent some types of colon cancer and breast cancer from growing in test tubes.
The oil also appeared to inhibit the growth of some lung cancer and prostate cancer cells. Much of the research in cancer comes from test tubes or animal models, so people should view the results with caution and never use oils as a replacement for medical treatment.
Oregano oil comes in capsules and as a liquid. It is available for purchase in most health food stores and online.
The strength of each oil may vary, so it is important to follow the manufacturer’s instructions or work with a qualified healthcare practitioner to determine the safest dose.
People who do not enjoy the taste of oregano should choose the capsules, which they can swallow without tasting the oil.
To use oregano oil topically for skin issues, dilute one or two drops in a carrier oil. A person can then apply this mixture directly to the skin.
Be sure not to take too much oregano oil, as it is very potent. It is best to use it sparingly under the guidance of a healthcare practitioner.
There is significant risk of burning internal tissue if a person takes the oil orally. Always follow the manufacturer’s guidelines.
Do not use oregano oil on children or infants. Pregnant or breastfeeding women and people with diabetes should also refrain from using it.
Oregano oil can interfere with some medications, including lithium and diuretics. Also, it is possible to be allergic to the oil.